 Nov 1 2022
Recent article published in Molecular Oncology with MedRod® implants i...
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Do you know the release rate of your drug delivery system? Is it based on assumption or real measurements?When generating hormone dependent PDX, xenograft or syngeneic tumor studies it is vital to know exact release rate of hormones to avoid adverse effects and to promote optimal tumor growth.
|  | ServicesWith our wide range of experience and analysis equipment we provide services for pharmaceutical industry and other research facilities. The services are offered either in connection to slow-release implant development or separately. Feasibility studies for implant applications
- Formulation of customer´s compounds through our extensive experience in the field of polymer-based drug delivery systems
- Planning and conducting in vitro and in vivo studies for long-term delivery of active ingredients from medical polymer implants
In vivo services
- Quick and cost-effective in vivo pharmacokinetic (PK) studies in rodents. Rapid turnaround of PK data (such as AUC, Cmax, and Tmax)
- In close collaboration with trusted partners, bigger animal models and pharmacodynamic (PD) studies
Analytical support for preclinical studies
- Method transfer, optimization, development and validation
- Drug dissolution studies of implants and injectable depots for new APIs and excipients
- Bioanalytical measurements of in vivo serum/plasma/tissue samples, in vitro dissolution samples
- Sample identification, microscopic evaluation
Technology Platforms
- HPLC-UV/Vis, ELISA assays, by collaboration LC MS/MS, ALPHA FTIR Spectrometer, 1-100x Microscopy
Consultation
- Strategic consulting related to core business areas
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