Our Services
Explore our services and see what we can do for you.
services
Custom Sustained-Release Implant Development
PreclinApps specializes in implantable drug delivery systems offering off the shelf but also customized drug dosing for research purposes: compound and target-release-rate assessment, polymer and formulation selection, prototype implant manufacture, in vitro release testing, dose and geometry optimization, preclinical-use material supply, study-specific technical consultation.
The services are offered either in connection to sustained-release MedRod® implant development or separately according to customer’s needs.
Implantable drug delivery systems
At PreclinApps, we are dedicated to advancing implantable chronic drug dosing for the pharmaceutical industry and research institutions. We provide high-quality, reliable solutions designed to meet the evolving needs of pharmaceutical research and development.
Our expertise spans a wide range of R&D services, from early-stage drug formulation to sustained-release implantable drug delivery technologies. Through our implantable drug delivery systems, clients gain access to precision-engineered biocompatible implants that enable steady, long-term release of active compounds.
Feasibility studies for implant applications
PreclinApps offers formulation of customer´s compound or investigational drug to an implantable drug delivery system through our extensive experience in polymer-based drug delivery systems field. PreclinApps targets to steady and sustained long term delivery of customer’s compounds from an biocompatible implant that has drug release controlling membrane. This kind of steady release in dosing can’t be achieved with matrix type compressed implant pellets.
Our implant technology is designed to deliver consistent therapeutic effects over extended periods, reducing the need for frequent dosing and enhancing patient outcomes. Unlike traditional matrix-type compressed implants, our biocompatible implants incorporate advanced drug release control membranes that provide a steady and sustained release profile, ensuring maximum therapeutic efficacy.
Whether developing a novel drug delivery system or optimizing an existing formulation, PreclinApps offers proven expertise and a commitment to delivering the most effective implantable drug delivery solutions in the industry.
Basic feasibility study steps for client’s molecule
- Literature evaluation of API / Polymer matrix compatibility
- Study design
- Mixing of drug (10%) with polymer matrices
- Curing of API/polymer formulation in wanted design
- Evaluation of curing compatibility – elasticity / extractables /visual
- Develop method for in vitro dissolution (Vial/volume/Media)
- Develop method for HPLC analysis
- Initial dissolution study – 2 weeks (4h, 1d, 4d, 7d, 14d)
- Evaluation of applicability for desired application
- Reporting
About our consulting service
PreclinApps can aid your research by guiding in the selection of animal model with suitable polymer and dosage selection.
How can we help you?
Feel free to reach out to us with any MedRod product inquiries or collaboration opportunities!